McDonald's in Durham, North Carolina

Updated 2026

There are 13 McDonald's locations in Durham, North Carolina.

About McDonald's in Durham

McDonald's in Durham provides locals with a convenient spot for quick bites and family meals, offering everything from classic burgers to breakfast all day long. With nine locations scattered throughout the city, McDonald's ensures that residents and visitors can easily grab a meal or snack without breaking the bank.

McDonald's - Durham

1010 N Miami Blvd, Durham, NC 27703

919-530-8510

Monday-Sunday: 6:00am-9:00pm

McDonald's - Durham

106 Bryan Ctr, Durham, NC 27708

919-668-2404

Open 24 Hours

McDonald's - Durham

1708 New Raleigh Hwy, Durham, NC 27703

919-596-7706

Monday-Thursday: 5:00am-12:00am, Friday-Saturday: 5:00am-1:00am, Sunday: 5:00am-12:00am

McDonald's - Durham

2010 N Roxboro Road, Durham, NC 27704

919-220-4074

Open 24 Hours

McDonald's - Durham

204 W Nc Hwy 54, Durham, NC 27713

919-806-1345

Monday-Wednesday: 5:00am-12:00am, Thursday-Saturday: 5:00am-3:45am, Sunday: 5:00am-12:00am

McDonald's - Durham

2700 Guess Rd, Durham, NC 27705

919-471-9669

Monday-Thursday: 5:30am-12:00am, Friday-Saturday: 5:30am-1:00am, Sunday: 5:30am-12:00am

McDonald's - Durham

3117 Tower Blvd, Durham, NC 27707

919-490-6209

Monday-Wednesday: 5:00am-12:00am, Thursday-Sunday: 5:00am-4:00am

McDonald's - Durham

3533 Hillsborough Rd, Durham, NC 27705

919-383-6989

Monday-Sunday: 5:00am-11:00pm

McDonald's - Durham

3844 S Roxboro Street, Durham, NC 27713

919-484-0953

Monday-Sunday: 5:00am-11:00pm

McDonald's - Durham

4301 N Roxboro Rd, Durham, NC 27704

919-477-7954

Monday-Thursday: 5:30am-11:00pm, Friday-Saturday: 5:30am-12:00am, Sunday: 5:30am-11:00pm

McDonald's - Durham

4717 Apex Hwy, Durham, NC 27713

336-437-5466

Monday-Wednesday: 5:00am-1:00am, Thursday-Sunday: 5:00am-2:00am

McDonald's - Durham

5277 N Roxboro Road, Durham, NC 27712

919-471-9645

Monday-Thursday: 5:30am-11:00pm, Friday-Saturday: 5:30am-12:00am, Sunday: 5:30am-11:00pm

McDonald's - Durham

5507 S Miami Blvd, Durham, NC 27703

919-474-8809

Open 24 Hours

Other Stores in Durham

Starbucks 20 Public Storage 12 CVS 10 Walgreens 10 Dollar Tree 9 Family Dollar 8 Dollar General 7 AutoZone 7 Panera Bread 7 Wendy's 6 Advance Auto Parts 6 Pizza Hut 5 Dunkin' Donuts 5 AT&T 4 bareMinerals 4 Rent-A-Center 4 GameStop 3 Verizon Wireless 2 Walmart 2 Ross 2

McDonald's in Durham

There are 13 McDonald's locations in Durham, North Carolina. Each listing includes the store address, phone number, and opening hours. Select a McDonald's store in Durham for full details, a map, and directions.