McDonald's in Pilot Knob

McDonald's at 201 Hwy 21 N, Pilot Knob, Missouri. Find store hours, phone number, driving directions and answers to frequently asked questions below.

Just off 201 Hwy 21 N, this McDonald's in Pilot Knob, Missouri offers a familiar menu of burgers, fries, and shakes at budget-friendly prices. The restaurant provides quick service through its drive-thru window as well as dine-in seating for customers. Hours may vary, so it’s best to call ahead or check their social media pages.

Address & Contact

McDonald's

201 Hwy 21 N,
Pilot Knob, MO 63650

573-546-7608

Store information verified in 2026

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Store Hours

Monday5:00am - 11:00pm

Tuesday5:00am - 11:00pm

Wednesday5:00am - 11:00pm

Thursday5:00am - 11:00pm

Friday5:00am - 12:00am

Saturday5:00am - 12:00am

Sunday5:00am - 11:00pm

Store hours may vary. Please call to confirm.

Drive-Thru Hours

Monday5:00am - 11:00pm

Tuesday5:00am - 11:00pm

Wednesday5:00am - 11:00pm

Thursday5:00am - 11:00pm

Friday5:00am - 11:00pm

Saturday5:00am - 11:00pm

Sunday5:00am - 11:00pm

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Location & Map

McDonald's - Pilot Knob is located on 201 Hwy 21 N, Pilot Knob, MO 63650

Drive-Thru Free Wi-Fi Indoor Dining Delivery Mobile Order & Pay Gift Cards

Delivery available via Uber Eats.

Nearby Locations

McDonald's - Farmington
1700 W Columbia St, Farmington, MO 63640

14 miles

McDonald's - Farmington
207 W Karsch Blvd, Farmington, MO 63640

16 miles

McDonald's - Desloge
411 N State Street, Desloge, MO 63628

19 miles

McDonald's - Potosi
800 E High St, Potosi, MO 63664

22 miles

McDonald's - Piedmont
1020 S Main St, Piedmont, MO 63957

33 miles

McDonald's - Salem
202 E. Scenic Rivers Blvd., Salem, MO 65560

48 miles

Frequently Asked Questions

How can I get directions to the McDonald's on Hwy 21 N?

For directions and more information about this location, you may call the restaurant directly at 573-546-7608.

What are the drive-thru hours for McDonald's at 201 Hwy 21 N, Pilot Knob?

Drive-thru hours: Monday 5:00am - 11:00pm, Tuesday 5:00am - 11:00pm, Wednesday 5:00am - 11:00pm, Thursday 5:00am - 11:00pm, Friday 5:00am - 11:00pm, Saturday 5:00am - 11:00pm, Sunday 5:00am - 11:00pm.

Does McDonald's at 201 Hwy 21 N, Pilot Knob offer delivery?

Yes, this McDonald's is available for delivery through Uber Eats.

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