McDonald's at 1503 Highway 43 S, Picayune, Mississippi. Find store hours, phone number, driving directions and answers to frequently asked questions below.
Shoppers visiting Picayune can find this McDonald's at 1503 Highway 43 S, offering the convenience of drive-thru and cashless payment options. The restaurant is known for its consistent menu items such as burgers, chicken sandwiches, and breakfast meals. Located near Walgreens, it provides a familiar dining experience with quick service.
