McDonald's in Picayune, Mississippi

Updated 2026

There are 2 McDonald's locations in Picayune, Mississippi.

About McDonald's in Picayune

With 2 locations in Picayune, McDonald's provides locals with quick, affordable meals that are perfect for busy mornings or on-the-go lunches. Whether you're grabbing a breakfast sandwich to start your day or enjoying a classic Big Mac during your lunch break, these spots serve as convenient hubs for the community.

McDonald's - Picayune

1503 Highway 43 S, Picayune, MS 39466

601-798-8223

Please call directly for store hours, Store hours may vary due to seasonality.

PICAYUNE - Picayune

2301 Hwy 11 N, Picayune, MS 39466

601-799-2262

McDonald's locations & hours near Picayune

9 miles

HWY 11 & HWY 109 - Pearl River

64121 Hwy 1090, Pearl River, LA 70452

985-863-2314

15 miles

McDonald's - Slidell

100 Brownswitch Rd, Slidell, LA 70458

985-646-1081

16 miles

McDonald's - Slidell

3096 Gause Blvd E, Slidell, LA 70461

985-781-6644

17 miles

McDonald's - Slidell

1625 Gause Rd, Slidell, LA 70458

985-641-5847

18 miles

McDonald's - Slidell

2190 Gause Blvd W, Slidell, LA 70460

985-781-3080

19 miles

McDonald's - Slidell

370 Voters Rd, Slidell, LA 70461

985-649-6077

19 miles

McDonald's - Slidell

3301 Pontchartrain Drive, Slidell, LA 70458

985-639-1540

21 miles

POPLARVILLE, MS - Poplarville

4680 Hwy 53, Poplarville, MS 39470

601-795-8131

21 miles

McDonald's - Waveland

460 HWY 90 (Walmart #1195), Waveland, MS 39576

228-463-8919

22 miles

WAVELAND-US 90 - Waveland

302 Highway 90, Waveland, MS 39576

228-467-1294

22 miles

McDonald's - Bogalusa

250 Cumberland Street, Bogalusa, LA 70427

985-732-3973

24 miles

McDonald's - Mandeville

1687 Dove Park Rd, Mandeville, LA 70471

985-893-1089

26 miles

McDonald's - Covington

1007 Highway 190, Covington, LA 70433

985-892-6218

Other Stores in Picayune

Dollar General 11 Family Dollar 6 Walgreens 2 AutoZone 2 Stride Rite 1 Pizza Hut 1 Dollar Tree 1 Walmart 1 AT&T 1 Wendy's 1 Rent-A-Center 1 Verizon Wireless 1 CVS 1 Home Depot 1

McDonald's in Picayune

There are 2 McDonald's locations in Picayune, Mississippi. Each listing includes the store address, phone number, and opening hours. Select a McDonald's store in Picayune for full details, a map, and directions.