Home Depot in 2200 E Serene Ave

Home Depot at 2200 E Serene Ave, Las Vegas, Nevada. Find store hours, phone number, driving directions and answers to frequently asked questions below.

Located at 2200 E Serene Ave, this Home Depot is your go-to destination for all home improvement needs. From building materials and tools to appliances and expert advice, you can find everything you need right here. Just a short walk away, Signature Cafe offers a perfect spot to grab a coffee or snack during your shopping trip.

Quick facts about this Home Depot

Las Vegas has 9 Home Depot stores, and Nevada has 21.
The nearest other Home Depot is 4.3 mi away at 6025 S Pecos Rd.
Sunday hours (7am-8pm) are 3 hours shorter than on weekdays.
Within a quarter mile: Walmart (400 ft), Ross (450 ft), Petco (450 ft), Walgreens (500 ft).

Address & Contact

Home Depot

2200 E Serene Ave,
Las Vegas, NV 89123

702-837-4300

Store information verified in 2026

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Store Hours

Monday6:00am - 10:00pm

Tuesday6:00am - 10:00pm

Wednesday6:00am - 10:00pm

Thursday6:00am - 10:00pm

Friday6:00am - 10:00pm

Saturday6:00am - 10:00pm

Sunday7:00am - 8:00pm

Store hours may vary. Please call to confirm.

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Location & Map

Home Depot - Las Vegas is located on 2200 E Serene Ave, Las Vegas, NV 89123

Nearby Locations

Home Depot - Las Vegas
6025 S Pecos Rd, Las Vegas, NV 89120

4 miles

Home Depot - Henderson
1030 Sunset Rd, Henderson, NV 89014

5 miles

Home Depot - Las Vegas
7015 Arroyo Crossing Pkwy 3, Las Vegas, NV 89113

7 miles

Home Depot - Las Vegas
4750 S Decatur Blvd, Las Vegas, NV 89103

7 miles

Home Depot - Las Vegas
1401 S Lamb Blvd, Las Vegas, NV 89104

9 miles

Home Depot - Las Vegas
4195 S Fort Apache Rd, Las Vegas, NV 89147

11 miles

Frequently Asked Questions

Are weekend hours different at this Home Depot location?

Yes, on Sundays, this Home Depot opens at 7:00am and closes at 8:00pm, which is an hour later than weekdays but earlier than the weekday closing time.

How can I get directions to the Home Depot store at 2200 E Serene Ave?

You can easily find directions to 2200 E Serene Ave using your preferred navigation app or by searching online for "Home Depot near me.

What are the hours for Home Depot at 2200 E Serene Ave, Las Vegas?

Monday-Saturday: 6:00am-10:00pm, Sunday: 7:00am-8:00pm

Is Home Depot in Las Vegas open on Sunday?

Yes, Home Depot at 2200 E Serene Ave in Las Vegas is open on Sunday: 7:00am - 8:00pm.

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