Home Depot at 2000 Hwy 43 South, Picayune, Mississippi. Find store hours, phone number, driving directions and answers to frequently asked questions below.
Shoppers visiting Picayune can find this Home Depot at 2000 Hwy 43 South, offering everything from building materials to tools and appliances. The store is open late into the evening, making it convenient for customers to drop by after work or on weekends. For those looking for holiday decorations, the store features a wide selection of Martha Stewart Living products, artificial trees, and live trees.
