Home Depot in Hyannis, Massachusetts

Updated 2026

Find Home Depot in Hyannis, Massachusetts.

About Home Depot in Hyannis

Hyannis's Home Depot store offers residents a comprehensive selection of building materials, tools, and appliances tailored to Cape Cod’s unique home improvement needs, making it a go-to destination for both DIY enthusiasts and professional contractors in the area.

Home Depot - Hyannis

65 Independence Drive, Hyannis, MA 02601

508-778-8948

Mon-Sat: 6:00am-9:00pm, Sun: 8:00am-7:00pm, Store hours may vary due to seasonality. Product Highligts Holiday HOLIDAY DECORATIONS Martha Stewart Living Holiday Artificial Trees Live Trees

Home Depot locations & hours near Hyannis

19 miles

Home Depot - East Wareham

2994 Cranberry Hwy, East Wareham, MA 02538

508-291-7051

25 miles

Home Depot - Plymouth

39 Long Pond Road, Plymouth, MA 02360

508-830-6702

41 miles

Home Depot - Taunton

899 County Street, Taunton, MA 02780

508-823-0960

42 miles

Home Depot - Bridgewater

1453 Pleasant Street, Bridgewater, MA 02324

508-697-0327

44 miles

Home Depot - Somerset

535 Grand Army Hwy, Somerset, MA 02726

508-646-9053

45 miles

Home Depot - Brockton

715 Crescent Street, Brockton, MA 02302

508-427-9970

45 miles

Home Depot - Rockland

1149 Hingham St, Rockland, MA 02370

781-871-6200

50 miles

Home Depot - Avon

60 Stockwell Dr, Avon, MA 02322

508-580-0600

52 miles

Home Depot - Middletown

878 West Main Rd, Middletown, RI 02842

401-845-5092

52 miles

Home Depot - Quincy

465 Centre St, Quincy, MA 02169

617-479-0707

53 miles

Home Depot - Mansfield

390 West St, Mansfield, MA 02048

508-337-2050

54 miles

Home Depot - Seekonk

95 Highland Ave, Seekonk, MA 02771

508-336-2563

54 miles

Home Depot - Quincy

177 Willard St, Quincy, MA 02169

617-376-0380

56 miles

Home Depot - South Attleboro

1100 Newport Ave, South Attleboro, MA 02703

508-761-4001

Other Stores in Hyannis

Dunkin' Donuts 4 CVS 3 Starbucks 3 Avis Car Rental 2 Sephora 2 Sunglass Hut 2 Wendy's 2 Verizon Wireless 2 AT&T 2 McDonald's 2 DSW Designer Shoe Warehouse 1 Ulta Beauty 1 Aeropostale 1 Advance Auto Parts 1 Staples 1 Target 1 Victoria's Secret 1 T.J.Maxx 1 Olive Garden 1 Marshalls 1

Home Depot in Hyannis

Find Home Depot in Hyannis, Massachusetts. Each listing includes the store address, phone number, and opening hours. Select a Home Depot store in Hyannis for full details, a map, and directions.