CVS in Columbia, South Carolina

Updated 2026

There are 14 CVS locations in Columbia, South Carolina.

About CVS in Columbia

CVS in Columbia provides essential health and wellness services alongside a variety of beauty and convenience products, catering specifically to the needs of local residents. With 16 convenient locations throughout the city, CVS ensures that Columbia shoppers have easy access to necessary medications and daily essentials.

CVS - Columbia

1002 SAMS CROSSING RD, Columbia, SC 29229

803-788-0535

Monday-Sunday: 8:00am-10:00pm

CVS - Columbia

100 OUTLET POINT BLVD, Columbia, SC 29210

803-772-0403

Monday-Sunday: 8:00am-9:00pm

CVS Pharmacy #16662 - Columbia

10204 TWO NOTCH RD, Columbia, SC 29229

803-788-0951

CVS - Columbia

121 CLEMSON RD, Columbia, SC 29229

803-419-4002

Monday-Thursday: 7:00am-11:00pm, Friday-Saturday: 7:00am-12:00am, Sunday: 7:00am-11:00pm

CVS Pharmacy #16556 - Columbia

134 HARBISON BLVD, Columbia, SC 29212

803-407-0328

CVS - Columbia

3312 DEVINE STREET, Columbia, SC 29205

803-748-8588

Monday-Friday: 7:00am-10:00pm, Saturday-Sunday: 8:00am-10:00pm

CVS - Columbia

3595 HARDEN ST, Columbia, SC 29203

803-799-1217

Monday-Friday: 9:00am-8:00pm, Saturday-Sunday: 10:00am-5:00pm

CVS - Columbia

3700 TWO NOTCH ROAD, Columbia, SC 29204

803-786-0158

Monday-Friday: 8:00am-9:00pm, Saturday-Sunday: 9:00am-9:00pm

CVS - Columbia

4310 HARDSCRABBLE ROAD, Columbia, SC 29229

803-865-6682

Monday-Sunday: 8:00am-10:00pm

CVS - Columbia

4627 NORTH MAIN STREET, Columbia, SC 29203

803-786-1106

Monday-Saturday: 8:00am-9:00pm, Sunday: 9:00am-7:00pm

CVS - Columbia

4711-5 FOREST DRIVE, Columbia, SC 29206

803-787-0186

Monday-Friday: 9:00am-8:00pm, Saturday: 9:00am-6:00pm, Sunday: 10:00am-6:00pm

CVS Pharmacy #17041 - Columbia

6090A GARNERS FERRY RD, Columbia, SC 29209

803-783-3752

CVS - Columbia

7749 GARNERS FERRY RD,, Columbia, SC 29209

803-776-6605

Monday-Sunday: 8:00am-10:00pm

CVS Pharmacy #830 - Columbia

900 ASSEMBLY ST, Columbia, SC 29201

803-212-7016

Other Stores in Columbia

Dollar General 24 Family Dollar 19 McDonald's 15 Dollar Tree 14 Walgreens 14 Wendy's 11 Public Storage 10 AutoZone 8 Advance Auto Parts 7 Starbucks 6 Walmart 5 Burlington 4 Verizon Wireless 4 Game Stop 4 Pizza Hut 4 bareMinerals 4 Ulta Beauty 3 Dunkin' Donuts 3 Home Depot 3 Sephora 3

CVS in Columbia

There are 14 CVS locations in Columbia, South Carolina. Each listing includes the store address, phone number, and opening hours. Select a CVS store in Columbia for full details, a map, and directions.