CVS in Port Jefferson

CVS at 464 MAIN ST, Port Jefferson, New York. Find store hours, phone number, driving directions and answers to frequently asked questions below.

Shoppers visiting Port Jefferson can find this CVS at 464 Main Street, a convenient spot for all their health and beauty needs. The store is open late into the evening Monday through Friday and Saturday, offering extended hours to accommodate busy schedules. Just a short walk away from Red Shirt Comics, it's easy to combine shopping trips with visits to other local favorites.

Address & Contact

CVS

464 MAIN ST,
Port Jefferson, NY 11777

631-473-2914

Store information verified in 2026

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Store Hours

Monday8:00am - 9:00pm

Tuesday8:00am - 9:00pm

Wednesday8:00am - 9:00pm

Thursday8:00am - 9:00pm

Friday8:00am - 9:00pm

Saturday8:00am - 9:00pm

Sunday9:00am - 6:00pm

Store hours may vary. Please call to confirm.

Pharmacy Hours

Monday9:00am - 7:00pm

Tuesday9:00am - 7:00pm

Wednesday9:00am - 7:00pm

Thursday9:00am - 7:00pm

Friday9:00am - 7:00pm

Saturday10:00am - 6:00pm

Sunday11:00am - 5:00pm

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Location & Map

CVS - Port Jefferson is located on 464 MAIN ST, Port Jefferson, NY 11777

Pharmacy Photo Center Retail ATM SNAP/EBT Accepted Same-Day Delivery Buy Online, Pick Up In Store Immunizations

Nearby Locations

CVS - Port Jefferson Station
4331 NESCONSET HWY, Port Jefferson Station, NY 11776

2 miles

CVS - Setauket
682 RTE 25A, Setauket, NY 11733

2 miles

CVS - Miller Place
159-18 ROUTE 25A, Miller Place, NY 11764

3 miles

CVS Pharmacy #16549 - South Setauket
255 POND PATH RD, South Setauket, NY 11720

4 miles

CVS Pharmacy #3100 - Coram
1710 ROUTE 112, Coram, NY 11727

4 miles

CVS - Selden
822 MIDDLE COUNTRY RD, Selden, NY 11784

5 miles

Frequently Asked Questions

What are the regular hours for this CVS store in Port Jefferson?

This CVS is open Monday through Friday from 8am to 9pm and Saturday from 8am to 9pm.

Does this CVS have different hours on Sunday compared to weekdays?

Yes, on Sundays the store opens at 9am and closes at 6pm, which is earlier than weekday hours.

How can I get in touch with this CVS if I need help or want directions to the store?

You can call the Port Jefferson CVS at (631) 473-2914 for assistance or direction inquiries.

What are the pharmacy hours for CVS at 464 MAIN ST, Port Jefferson?

Pharmacy hours: Monday 9:00am - 7:00pm, Tuesday 9:00am - 7:00pm, Wednesday 9:00am - 7:00pm, Thursday 9:00am - 7:00pm, Friday 9:00am - 7:00pm, Saturday 10:00am - 6:00pm, Sunday 11:00am - 5:00pm.

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