McDonald's in Cape Girardeau, Missouri

Updated 2026

There are 3 McDonald's locations in Cape Girardeau, Missouri.

About McDonald's in Cape Girardeau

Serving the Cape Girardeau community, McDonald's provides quick and affordable meal options at three convenient locations, catering to the bustling needs of students, workers, and families alike in this vibrant Missouri city. Whether you're grabbing a morning coffee or enjoying a family dinner on the go, these local spots are tailored to serve the diverse tastes and schedules of Cape Girardeau residents.

CAPE GIRAR - Cape Girardeau

1701 N Kings Highway, Cape Girardeau, MO 63701

573-803-0540

McDonald's - Cape Girardeau

1925 Broadway Street, Cape Girardeau, MO 63701

573-334-6664

Please call directly for store hours, Store hours may vary due to seasonality.

McDonald's - Cape Girardeau

3419 Williams, Cape Girardeau, MO 63701

573-335-9407

Please call directly for store hours, Store hours may vary due to seasonality.

McDonald's locations & hours near Cape Girardeau

11 miles

JACKSN-HWY 61 - Jackson

2220 Hwy 61 E, Jackson, MO 63755

573-243-7886

16 miles

McDonald's - Benton

6415 State Hwy 77, Benton, MO 63736

573-545-3158

20 miles

ANNA - Anna

510 E Vienna, Anna, IL 62906

618-833-7922

22 miles

McDonald's - Marble Hill

315 Presnell, Marble Hill, MO 63764

573-238-4747

24 miles

ADVANCE MO - Advance

33468 State Hwy 25, Advance, MO 63730

573-722-3500

30 miles

McDonald's - Sikeston

1301 S Main, Sikeston, MO 63801

573-471-3111

30 miles

McDonald's - Miner

2605 E Malone, Miner, MO 63801

573-481-1100

31 miles

McDonald's - Perryville

1302 S Perryville Blvd, Perryville, MO 63775

573-547-1650

31 miles

CHARLESTON RELO - Charleston

2071 S Main Street, Charleston, MO 63834

573-683-6060

31 miles

McDonald's - Carbondale

1920 S Illinois Ave, Carbondale, IL 62901

618-457-7344

32 miles

MURPHYSBORO RELO - Murphysboro

105 Muddy Monster Rd, Murphysboro, IL 62966

618-687-1171

34 miles

McDonald's - Carbondale

1396 E Main St, Carbondale, IL 62901

618-457-5220

Other Stores in Cape Girardeau

Dollar General 6 CVS 3 Walmart 3 Starbucks 3 AutoZone 2 bareMinerals 2 AT&T 2 Pizza Hut 2 Dollar Tree 2 Sephora 1 Ulta Beauty 1 JCPenny 1 Staples 1 PetSmart 1 Target 1 Petco 1 Claire's 1 Victoria's Secret 1 Avis Car Rental 1 Sleep Number 1

McDonald's in Cape Girardeau

There are 3 McDonald's locations in Cape Girardeau, Missouri. Each listing includes the store address, phone number, and opening hours. Select a McDonald's store in Cape Girardeau for full details, a map, and directions.